Intestinal transplantation in children: five-year experience.

Between 1990 to 1995, 41 children received 44 intestinal transplants under tacrolimuslsteroid immunosuppression and included the isolated small bowel (S8) (n = 10), liver/small bowel (LS8) (n = 27) and multivisceral (MV) (n = 7) allografts. There were 19 males and 22 females with ages ranging between 0.5 to 18 years (mean of 4.2 years). Twenty grafts contained a segment of large bowel which was distributed among all three recipient cohorts. The last four patients, and one additional patient undergoing intestinal rctransplantation were also given unaltered adjuvant donor bone marrow. The rational and methods of simultaneous bone marrow infusion in solid organ transplantation have been reported elsewhere in this issue.2 Immunosuppression, donor and recipient surgical procedures and nutritional management were as previously described.3